4-(二甲基氨基)-3-丁炔-2-酮合成路线 （共 8 条）
反应条件
potassium tert-butylate in tetrahydrofuran; tert-butyl alcohol T=-5 - 0°C; 1 h;
参考文献
Ostroumov, I. G.; Tsil'ko, A. E.; Maretina, I. A.; Petrov, A. A.
Journal of Organic Chemistry USSR (English Translation), 1987 , vol. 23, # 8 p. 1467 - 1474
Zhurnal Organicheskoi Khimii, 1987 , vol. 23, # 8 p. 1635 - 1643
反应条件
1: 1) Br2, 2) (C2H5)3N / 1) CH2Cl2, -10 to 15 deg C, 2) (C2H5)2O, -10 to 15 deg C, 1 h 2: 60 percent / (CH3)3COK / tetrahydrofuran; 2-methyl-propan-2-ol / 1 h / -5 - 0 °C View Scheme
参考文献
Ostroumov, I. G.; Tsil'ko, A. E.; Maretina, I. A.; Petrov, A. A.
Journal of Organic Chemistry USSR (English Translation), 1987 , vol. 23, # 8 p. 1467 - 1474
Zhurnal Organicheskoi Khimii, 1987 , vol. 23, # 8 p. 1635 - 1643
反应条件
1: (i) Br2, (ii) Et3N 2: KOtBu View Scheme
参考文献
Gais,H.-J. et al.
Helvetica Chimica Acta, 1969 , vol. 52, p. 2641 - 2657
参考文献
Gais, H.-J.
Tetrahedron Letters, 1984 , vol. 25, # 3 p. 273 - 276
反应条件
in tetrahydrofuran
T=65 - 70°C; 3 h; argon atmosphere;
参考文献
Ostroumov, I. G.; Tsil'ko, A. E.; Maretina, I. A.; Petrov, A. A.
Journal of Organic Chemistry USSR (English Translation), 1988 , vol. 24, # 6 p. 1049 - 1055
Zhurnal Organicheskoi Khimii, 1988 , vol. 24, # 6 p. 1165 - 1172
参考文献
Niederhauser,A. et al.
Helvetica Chimica Acta, 1973 , vol. 56, p. 944 - 958
反应条件
in tetrahydrofuran; dichloromethane
Heating; Yield given. Yields of byproduct given;
参考文献
Ostroumov, I. G.; Tsil'ko, A. E.; Maretina, I. A.; Petrov, A. A.
Journal of Organic Chemistry USSR (English Translation), 1987 , vol. 23, # 8 p. 1467 - 1474
Zhurnal Organicheskoi Khimii, 1987 , vol. 23, # 8 p. 1635 - 1643
反应条件
in tetrahydrofuran; dichloromethane
Heating; Yield given. Yields of byproduct given;
参考文献
Ostroumov, I. G.; Tsil'ko, A. E.; Maretina, I. A.; Petrov, A. A.
Journal of Organic Chemistry USSR (English Translation), 1987 , vol. 23, # 8 p. 1467 - 1474
Zhurnal Organicheskoi Khimii, 1987 , vol. 23, # 8 p. 1635 - 1643
