[(N,N'-dimethyl-N,N'-bis(2-pyridylmethyl)-1,2-diaminoethane)Fe(triflate)2]; dihydrogen peroxide; acetic acid in ethyl acetate; acetonitrile T=40°C; 72 h;

[(N,N'-dimethyl-N,N'-bis(2-pyridylmethyl)-1,2-diaminoethane)Fe(triflate)2]; dihydrogen peroxide; acetic acid in ethyl acetate; acetonitrile T=40°C; 72 h;

1.1: SnCl2; EtOH / Heating 2.1: NEt3 / CH2Cl2 3.1: s-BuLi / tetrahydrofuran / -20 - 0 °C 4.1: aq. HCl / 1,2-dimethoxy-ethane / Heating 5.1: BBr3 / CH2Cl2 6.1: imidazole / dimethylformamide / 0 °C 7.1: 76 percent / tetrahydrofuran; hexane / -20 °C 8.1: i-Pr2NEt / toluene / -25 - 20 °C 9.1: n-Bu4NF / tetrahydrofuran 9.2: chiral phase SCFC View Scheme

1.1: NEt3 / CH2Cl2 2.1: s-BuLi / tetrahydrofuran / -20 - 0 °C 3.1: aq. HCl / 1,2-dimethoxy-ethane / Heating 4.1: BBr3 / CH2Cl2 5.1: imidazole / dimethylformamide / 0 °C 6.1: 76 percent / tetrahydrofuran; hexane / -20 °C 7.1: i-Pr2NEt / toluene / -25 - 20 °C 8.1: n-Bu4NF / tetrahydrofuran 8.2: chiral phase SCFC View Scheme

1.1: s-BuLi / tetrahydrofuran / -20 - 0 °C 2.1: aq. HCl / 1,2-dimethoxy-ethane / Heating 3.1: BBr3 / CH2Cl2 4.1: imidazole / dimethylformamide / 0 °C 5.1: 76 percent / tetrahydrofuran; hexane / -20 °C 6.1: i-Pr2NEt / toluene / -25 - 20 °C 7.1: n-Bu4NF / tetrahydrofuran 7.2: chiral phase SCFC View Scheme

1.1: BBr3 / CH2Cl2 2.1: imidazole / dimethylformamide / 0 °C 3.1: 76 percent / tetrahydrofuran; hexane / -20 °C 4.1: i-Pr2NEt / toluene / -25 - 20 °C 5.1: n-Bu4NF / tetrahydrofuran 5.2: chiral phase SCFC View Scheme

1.1: imidazole / dimethylformamide / 0 °C 2.1: 76 percent / tetrahydrofuran; hexane / -20 °C 3.1: i-Pr2NEt / toluene / -25 - 20 °C 4.1: n-Bu4NF / tetrahydrofuran 4.2: chiral phase SCFC View Scheme

1.1: 76 percent / tetrahydrofuran; hexane / -20 °C 2.1: i-Pr2NEt / toluene / -25 - 20 °C 3.1: n-Bu4NF / tetrahydrofuran 3.2: chiral phase SCFC View Scheme

1.1: i-Pr2NEt / toluene / -25 - 20 °C 2.1: n-Bu4NF / tetrahydrofuran 2.2: chiral phase SCFC View Scheme

1: With tetrabutyl ammonium fluoride in tetrahydrofuran 2: chiral phase SCFC;