tetrabutyl ammonium fluoride in tetrahydrofuran T=20°C; 1 h;

pyridine T=20°C; 12 h;

4 A molecular sieve; 2,3-dicyano-5,6-dichloro-p-benzoquinone in dichloromethane T=20°C; Etherification; 0.166667 h;

4 A molecular sieve; 2,3-dicyano-5,6-dichloro-p-benzoquinone in dichloromethane T=20°C; 0.333333 h;

1: 93 percent / Et3N; DMAP; molecular sieves 4 Angstroem / CH2Cl2 / 8 h / 20 °C 2: 92 percent / molecular sieves 4 Angstroem; DDQ / CH2Cl2 / 0.17 h / 20 °C View Scheme

1: 85 percent / CuSO4 / 25 h / Ambient temperature 2: 90 percent / 75percent AcOH / 24 h / Ambient temperature 3: 95 percent / pyridine / 16 h View Scheme

1: 90 percent / 75percent AcOH / 24 h / Ambient temperature 2: 95 percent / pyridine / 16 h View Scheme

暂无反应条件数据

sodium hydrogen sulphate; silica gel in methanol; dichloromethane T=20°C; 2 h;

1.1: Dess-Martin periodane / dichloromethane / 20 °C / |Inert atmosphere 2.1: sodium hydride / mineral oil; tetrahydrofuran / 0.5 h / -10 °C / |Inert atmosphere 2.2: |Inert atmosphere 3.1: trifluoroacetic acid / dichloromethane; water / 0.5 h / 20 °C / |Inert atmosphere 4.1: pyridine / 3.17 h / 0 - 20 °C / |Inert atmosphere 5.1: triethylamine / dichloromethane / 1 h / 20 °C / |Inert atmosphere 6.1: tetrakis(triphenylphosphine) palladium(0) / tetrahydrofuran / |Inert atmosphere; |Reflux 7.1: trichlorophosphate / 2 h / 20 - 50 °C / |Inert atmosphere 8.1: tert-butylamine borane / dichloromethane / 0.33 h / 20 °C / |Inert atmosphere 8.2: 2 h / |Inert atmosphere; |Reflux View Scheme