N-(4-硝基苄基)-1-金刚烷胺合成路线 （共 4 条）
反应条件
sodium cyanoborohydride in methanol T=20°C; Inert atmosphere;
参考文献
Wang, Jizhou; Ma, Chunlong; Wang, Jun; Jo, Hyunil; Canturk, Belgin; Fiorin, Giacomo; Pinto, Lawrence H.; Lamb, Robert A.; Klein, Michael L.; DeGrado, William F.
Journal of Medicinal Chemistry, 2013 , vol. 56, # 7 p. 2804 - 2812
反应条件
sodium tetrahydroborate in ethanol a) -78 deg C, 10 min, b) RT, 30 min; Yield given;
参考文献
Sar, Cecilia P.; Hideg, Eva; Vass, Imre; Hideg, Kalman
Bioorganic and Medicinal Chemistry Letters, 1998 , vol. 8, # 4 p. 379 - 384
反应条件
1: p-TsOH / toluene / 2 h / Heating 2: NaBH4 / ethanol / a) -78 deg C, 10 min, b) RT, 30 min View Scheme
参考文献
Sar, Cecilia P.; Hideg, Eva; Vass, Imre; Hideg, Kalman
Bioorganic and Medicinal Chemistry Letters, 1998 , vol. 8, # 4 p. 379 - 384
反应条件
1: p-TsOH / toluene / 2 h / Heating 2: NaBH4 / ethanol / a) -78 deg C, 10 min, b) RT, 30 min View Scheme
参考文献
Sar, Cecilia P.; Hideg, Eva; Vass, Imre; Hideg, Kalman
Bioorganic and Medicinal Chemistry Letters, 1998 , vol. 8, # 4 p. 379 - 384
