bis(1,5-cyclooctadiene)nickel (0); potassium phosphate; tri-cyclo-hexyl-phosphine in tetrahydrofuran T=25°C; 12 h; Inert atmosphere;

bis(1,5-cyclooctadiene)nickel (0); potassium phosphate; tri-cyclo-hexyl-phosphine in tetrahydrofuran T=25°C; 12 h; Inert atmosphere;

1.1: sodium hydride / ethylene glycol dimethyl ether / 0.17 h / 0 - 20 °C / Inert atmosphere 1.2: 12 h / 0 - 20 °C / Inert atmosphere 2.1: potassium phosphate; bis(1,5-cyclooctadiene)nickel (0); tri-cyclo-hexyl-phosphine / tetrahydrofuran / 12 h / 25 °C / Inert atmosphere View Scheme

Multistep reaction;

Suzuki coupling;

Yield given. Multistep reaction;

aq. NaOH in tetrahydrofuran; diethyl ether; water