1: 1.) LiHMDS; 2.) PhSeCl / 1.) THF, 0 deg C; 2.) r.t. 2: 65 percent / NaH / tetrahydrofuran 3: KHMDS / tetrahydrofuran / 0 - 20 °C 4: hydrogen peroxide / tetrahydrofuran / 0 °C 5: 78 percent / hydrogen / PtO2 / ethanol / 360 h / 4137.2 Torr 6: 67 percent / aq. NaCl / dimethylsulfoxide / 2 h / 170 °C 7: TFA 8: Et3N 9: 50 percent / EtO2*BF3 / CH2Cl2 / Ambient temperature 10: 95 percent / sodium methoxide / 4 h / Ambient temperature 11: LiHMDS / tetrahydrofuran / 0 °C 12: 85 percent / 1.) 1N NaOH; 2.) HCl; 3.) Dowex50xB View Scheme