1: With iodine; dimethyl sulfoxide T=150°C; 0.333333 h; 2: With water; sodium hydrogencarbonate T=20°C;

1: With oxalyl dichloride; dimethyl sulfoxide in dichloromethane T=-78°C; 0.333333 h; Cooling with acetone-dry ice; 2: 6-(hydroxymethyl)nicotinonitrile in dichloromethane T=-78°C; 2 h; Cooling with acetone-dry ice; 3: With ammonium chloride; triethylamine more than 3 stages;

sodium periodate in tetrahydrofuran; water 2 h;

1: With ozone in dichloromethane T=-78°C; 0.5 h; 2: With dimethylsulfide in dichloromethane T=-78 - 20°C; 18 h;