2'-羟基-4',5'-二甲氧基苯乙酮合成路线 （共 21 条）
参考文献
Journal of the Chemical Society, , p. 848,857
参考文献
Journal of the Chemical Society, , p. 848,857
反应条件
hydrogen bromide; acetic acid
参考文献
Laumas et al.
Proceedings - Indian Academy of Sciences, Section A, 1957 , vol. 46, p. 343,346
反应条件
1: potassium carbonate / 100 °C 2: sodium methylate / 60 °C 3: water; sodium hydroxide / ethanol / 20 °C 4: boron tribromide / dichloromethane / 20 °C View Scheme
参考文献
Deng, Huayun; Fang, Ye
ACS Medicinal Chemistry Letters, 2012 , vol. 3, # 7 p. 550 - 554
反应条件
pyrrolidine in ethanol 12 h; Inert atmosphereReflux;
参考文献
Zhu, Mingyan; Kim, Myung Hee; Lee, Sanghee; Bae, Su Jung; Kim, Seong Hwan; Park, Seung Bum
Journal of Medicinal Chemistry, 2010 , vol. 53, # 24 p. 8760 - 8764
反应条件
1: 86 percent / 1.) lithium diisopropylamide / tetrahydrofuran / 1.) -30 deg C, 1 h, 2.) -40 deg C, 90 min 2: 90 percent / HCl / methanol / 2.5 h / Heating View Scheme
参考文献
Banerji, A.; Goomer, N. C.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1981 , vol. 20, # 2 p. 144 - 146
反应条件
1: 86 percent / 1.) lithium diisopropylamide / tetrahydrofuran / 1.) -30 deg C, 1 h, 2.) -40 deg C, 90 min 2: 90 percent / HCl / methanol / 2.5 h / Heating 3: 90 percent / LAH / diethyl ether / 3 h / Heating 4: 76 percent / p-toluenesulphonic acid / benzene / Heating View Scheme
参考文献
Banerji, A.; Goomer, N. C.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1981 , vol. 20, # 2 p. 144 - 146
参考文献
Smith; Haller
Journal of the American Chemical Society, 1934 , vol. 56, p. 237
反应条件
1: sodium
2: acetic acid; aqueous hydrochloric acid
3: aq.-ethanolic hydrochloric acid
View Scheme
参考文献
Jones et al.
Journal of the Chemical Society, 1949 , p. 562,565
反应条件
1: 86 percent / 1.) lithium diisopropylamide / tetrahydrofuran / 1.) -30 deg C, 1 h, 2.) -40 deg C, 90 min
2: 90 percent / HCl / methanol / 2.5 h / Heating
3: 90 percent / LAH / diethyl ether / 3 h / Heating
View Scheme
参考文献
Banerji, A.; Goomer, N. C.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1981 , vol. 20, # 2 p. 144 - 146
