5-甲基-3-苯基-4-异噁唑羧酸甲酯合成路线 （共 15 条）
反应条件
sodium hydroxide in methanol
参考文献
Green, Jeremy; Bemis, Guy; Grillot, Anne-Laure; Ledeboer, Mark; Salituro, Francesco G.; Harrington, Edmund; Gao, Huai; Baker, Christopher; Cao, Jingrong; Hale, Michael
Patent: US2003/149051 A1, 2003 ;
反应条件
1: water; sodium hydroxide / methanol / 1 h / pH 11 - 13 / Reflux 2: phosphorus pentachloride / 1 h / 45 °C View Scheme
参考文献
Ramana, P. Venkata; Reddy, A. Ram
Journal of Heterocyclic Chemistry, 2012 , vol. 49, # 3 p. 621 - 627
反应条件
1.1: NBS / CCl4 / 24 h / 40 - 45 °C / UV-irradiation 1.2: 93 percent / H2O / dimethylsulfoxide / 4 h / 80 °C 2.1: 82 percent / PCC / CH2Cl2 / 10 h / 20 °C View Scheme
参考文献
Roy, Amrendra K.; Rajaraman; Batra, Sanjay
Tetrahedron, 2004 , vol. 60, # 10 p. 2301 - 2310
反应条件
lithium aluminium tetrahydride in diethyl ether T=40°C; 1 h;
参考文献
Roy, Amrendra K.; Batra, Sanjay
Synthesis, 2003 , # 9 p. 1347 - 1356
反应条件
N-bromosuccinmide in tetrachloromethane
T=40 - 45°C; 24 h; UV-irradiation; Product distribution; Further Variations:TemperaturesReagentstime;
参考文献
Roy, Amrendra K.; Rajaraman; Batra, Sanjay
Tetrahedron, 2004 , vol. 60, # 10 p. 2301 - 2310
