2-氨基-5-溴-3-甲基苯甲酸合成路线 （共 7 条）
反应条件
N-bromosuccinmide in N,N-dimethyl-formamide T=70 - 80°C; 0.5 h;
参考文献
Journal of Agricultural and Food Chemistry, , vol. 60, # 44 p. 10942 - 10951
反应条件
1: With sodium hydroxide; sodium chloride in water 0.5 h; 2: With sodium hydroxide; dihydrogen peroxide in water 1.5 h;
参考文献
Journal of Organic Chemistry, , vol. 71, # 16 p. 5921 - 5929
反应条件
1: 99 percent / H2 / Pd/C / ethanol / 20 °C / 25857.4 Torr 2: 88 percent / HBr; DMSO / 16 h View Scheme
参考文献
Journal of Organic Chemistry, , vol. 71, # 16 p. 5921 - 5929
反应条件
1.1: 88 percent / Br2 / CHCl3 / 24 h / Heating 2.1: NaOH; NaCl / H2O / 0.5 h 2.2: 99 percent / H2O2; NaOH / H2O / 1.5 h View Scheme
参考文献
Journal of Organic Chemistry, , vol. 71, # 16 p. 5921 - 5929
反应条件
1.1: 74 percent / sodium sulfate; HCl / H2O / 0.03 h / Heating 2.1: 32 percent / sulfuric acid / 60 - 80 °C 3.1: 88 percent / Br2 / CHCl3 / 24 h / Heating 4.1: NaOH; NaCl / H2O / 0.5 h 4.2: 99 percent / H2O2; NaOH / H2O / 1.5 h View Scheme
参考文献
Journal of Organic Chemistry, , vol. 71, # 16 p. 5921 - 5929
反应条件
caesium carbonate in N,N-dimethyl-formamide T=20°C;
参考文献
WO2011/8572 A2, ;
Page/Page column 70-71 ;
WO 2011/008572 A2
参考文献
US5929097 A1, ;
US 5929097 A
