1-[4-(3-氨基苯基)-1-哌嗪]乙酮合成路线 （共 3 条）
反应条件
hydrogen; 5-palladium/activated carbon in ethanol; water
参考文献
NEUROSEARCH A/S
Patent: WO2006/111517 A1, 2006 ;
Location in patent: Page/Page column 15 ;
反应条件
hydrogen; palladium on activated carbon in ethanol P=2585.81 Torr; 2 h;
参考文献
SMITHKLINE BEECHAM CORPORATION
Patent: WO2007/18941 A2, 2007 ;
Location in patent: Page/Page column 85 ;
WO 2007/018941 A2
反应条件
1.1: K2CO3 / chlorobenzene / 24 h / Heating 1.2: 76 percent / conc. HCl / acetone 2.1: 99 percent / acetic acid / methanol / 20 °C 3.1: 85 percent / Ni-Raney; N2H4*H2O / methanol / 0 °C View Scheme
参考文献
Orus; Martinez; Perez; Oficialdegui; Del Castillo; Mourelle; Lasheras; Del Rio; Monge, Antonio
Pharmazie, 2002 , vol. 57, # 8 p. 515 - 518
