(R)-(-)-扁桃酸甲酯合成路线 （共 107 条）
反应条件
anhydrous magnesium perchlorate in acetonitrile T=20°C; 24 h;
参考文献
Tetrahedron, , vol. 59, # 26 p. 4911 - 4921
反应条件
anhydrous magnesium perchlorate in acetonitrile T=20°C; 24 h;
参考文献
Tetrahedron, , vol. 59, # 26 p. 4911 - 4921
反应条件
1: trimethylsilyl cyanide; benzaldehyde With [VO((R,R)-1,2-bis(3,5-tBu2-salicylideneamino)cyclohexanato)] in dichloromethane 2: methanol With hydrogenchloride in diethyl ether 3: With water; sodium hydrogencarbonate Title compound not separated from byproducts;
参考文献
Tetrahedron, , vol. 62, # 49 p. 11402 - 11412
反应条件
1: 1.) titanium tetrachloride / 1.) dichloromethane, -78 deg C, 25 min, 2.) -78 deg C, 45 min 2: 98 percent / pyridinium dichromate / CH2Cl2 / 18 h / 25 °C 3: 97 percent / hydrogen chloride / methanol / 16 h / 4 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 48, # 13 p. 2294 - 2295
反应条件
1: 98 percent / pyridinium dichromate / CH2Cl2 / 18 h / 25 °C 2: 97 percent / hydrogen chloride / methanol / 16 h / 4 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 48, # 13 p. 2294 - 2295
参考文献
Acta Chemica Scandinavica, , vol. 47, # 8 p. 823 - 825
ACH - Models in Chemistry, , vol. 135, # 4 p. 625 - 640
反应条件
water in diethyl ether 5 h; Ambient temperaturepig liver acetone powder, pH 8.0; Yield given. Title compound not separated from byproducts;
参考文献
Tetrahedron, , vol. 51, # 8 p. 2403 - 2416
反应条件
lipase in di-isopropyl ether T=35°C; Acetylation; resolution of racemate; 3 h; Title compound not separated from byproducts;
参考文献
Yamano, Toru; Kikumoto, Fumio; Yamamoto, Shozo; Miwa, Katsuhiko; Kawada, Mitsuru; Ito, Tatsuya; Ikemoto, Tomomi; Tomimatsu, Kiminori; Mizuno, Yukio
Chemistry Letters, 2000 , # 5 p. 448 - 449
反应条件
anhydrous magnesium perchlorate in acetonitrile T=30°C; 336 h; further reagents;
参考文献
Imanishi; Hamano; Yoshikawa; Iwata
Journal of the Chemical Society - Series Chemical Communications, 1988 , # 7 p. 473 - 475
反应条件
Bacillus licheniformis serine protease in 2,2,4-trimethylpentane; dimethyl sulfoxide T=37°C;
参考文献
Bioorganic Chemistry, , vol. 32, # 6 p. 504 - 515
