(R)-(-)-扁桃酸甲酯合成路线 （共 107 条）
参考文献
Journal of the American Chemical Society, , vol. 107, # 14 p. 4346 - 4348
反应条件
Zn(ClO4)2 in acetonitrile T=30°C; 336 h; further reagents;
参考文献
Imanishi; Hamano; Yoshikawa; Iwata
Journal of the Chemical Society - Series Chemical Communications, 1988 , # 7 p. 473 - 475
反应条件
anhydrous magnesium perchlorate in acetonitrile Reduction; 0.0833333 h;
参考文献
Tetrahedron Letters, , vol. 41, # 7 p. 1035 - 1038
反应条件
1: water; hydrogenchloride / 1,4-dioxane / 6 h / |Reflux 2: toluene-4-sulfonic acid / toluene / 2 h / |Reflux 3: lipase PS-30 / toluene / 144 h / 25 °C / |Molecular sieve; |Enzymatic reaction View Scheme
参考文献
Tetrahedron Letters, , vol. 55, # 14 p. 2290 - 2294
反应条件
1.1: sodium hydrogensulfite; water / diethyl ether / 2 h / 20 °C 1.2: 20 °C 2.1: water; hydrogenchloride / 1,4-dioxane / 6 h / |Reflux 3.1: toluene-4-sulfonic acid / toluene / 2 h / |Reflux 4.1: lipase PS-30 / toluene / 144 h / 25 °C / |Molecular sieve; |Enzymatic reaction View Scheme
参考文献
Tetrahedron Letters, , vol. 55, # 14 p. 2290 - 2294
反应条件
1: toluene-4-sulfonic acid / toluene / 2 h / |Reflux 2: lipase PS-30 / toluene / 144 h / 25 °C / |Molecular sieve; |Enzymatic reaction View Scheme
参考文献
Tetrahedron Letters, , vol. 55, # 14 p. 2290 - 2294
反应条件
anhydrous magnesium perchlorate in acetonitrile 240 h; dark; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of the American Chemical Society, , vol. 108, p. 1989
反应条件
sodium dihydrogenphosphate; Candida antarctica B lipase immobilized on polyethyleneimine in 1,4-dioxane; water T=25°C; pH=7; KineticsProduct distribution; Further Variations:ReagentspH-valuesTemperaturesSolventsionic strength;
参考文献
Tetrahedron Asymmetry, , vol. 13, # 12 p. 1337 - 1345
反应条件
1: 3,4,5,6-tetrachloro-1,2-benzoquinone; phenylacetyl chloride With benzoylquinidine; N-ethyl-N,N-diisopropylamine in tetrahydrofuran hetero Diels-Alder reaction; 2: methanol 3: With ammonium cerium(IV) nitrate Further stages. Title compound not separated from byproducts.;
参考文献
Chimia, , vol. 61, # 5 p. 240 - 246
反应条件
1: sulfuric acid / 3 h / Reflux 2: oxygen / chloroform / 28 h / 20 °C / Resolution of racemate View Scheme
参考文献
Advanced Synthesis and Catalysis, , vol. 353, # 8 p. 1234 - 1240
