1,2-二(苄氧基)-4,5-二溴苯合成路线 （共 7 条）
反应条件
bromine in dichloromethane T=0 - 20°C; 3 h;
参考文献
Hu, Mougang; Brasseur, Nicole; Zeki Yildiz; Van Lier, Johan E.; Leznoff, Clifford C.
Journal of Medicinal Chemistry, 1998 , vol. 41, # 11 p. 1789 - 1802
反应条件
potassium hydroxide; Aliquatreg; 336 T=120°C; 3 h;
参考文献
Hu, Mougang; Brasseur, Nicole; Zeki Yildiz; Van Lier, Johan E.; Leznoff, Clifford C.
Journal of Medicinal Chemistry, 1998 , vol. 41, # 11 p. 1789 - 1802
反应条件
potassium hydroxide in dimethyl sulfoxide T=-20°C; 8 h;
参考文献
Kalashnikova; Zhukov; Tomilova; Zefirov
Russian Chemical Bulletin, 2005 , vol. 54, # 9 p. 2094 - 2098
反应条件
1: 90 percent / 84percent aq. KOH, Aliquate 336 / dimethylformamide / 4 h / 120 °C 2: 92 percent / Br2 / CH2Cl2 / 3 h / 0 - 20 °C View Scheme
参考文献
Hu, Mougang; Brasseur, Nicole; Zeki Yildiz; Van Lier, Johan E.; Leznoff, Clifford C.
Journal of Medicinal Chemistry, 1998 , vol. 41, # 11 p. 1789 - 1802
反应条件
1: 90 percent / 84percent aq. KOH, Aliquate 336 / dimethylformamide / 4 h / 120 °C 2: 92 percent / Br2 / CH2Cl2 / 3 h / 0 - 20 °C View Scheme
参考文献
Hu, Mougang; Brasseur, Nicole; Zeki Yildiz; Van Lier, Johan E.; Leznoff, Clifford C.
Journal of Medicinal Chemistry, 1998 , vol. 41, # 11 p. 1789 - 1802
反应条件
1: 60 percent / dimethylformamide / 21 h / Heating 2: 91 percent / H2 / 10 percent Pd-C / ethyl acetate / 4 h / 20 °C View Scheme
参考文献
Cabezon, Beatriz; Quesada, Ernesto; Esperanza, Sagrario; Torres, Tomas
European Journal of Organic Chemistry, 2000 , # 15 p. 2767 - 2775
反应条件
in N,N-dimethyl-formamide T=150°C; 8 h;
参考文献
Cabezon, Beatriz; Quesada, Ernesto; Esperanza, Sagrario; Torres, Tomas
European Journal of Organic Chemistry, 2000 , # 15 p. 2767 - 2775
