醋酸(Z)-11-十四烯酯合成路线 （共 59 条）
反应条件
1.1: Nessler's reagent / ethanol; water / Cooling with ice
1.2: 4 h / 90 - 125 °C / Inert atmosphere
2.1: acetic acid / Reflux
3.1: Ni-P2/EDA
View Scheme
参考文献
Gansca, Lucia; Andreica, Adriana; Ciotlaus, Irina; Maxim, Sanda; Oprean, Ioan
Revue Roumaine de Chimie, 2011 , vol. 56, # 7 p. 705 - 709
反应条件
1.1: sodium hydride / dimethyl sulfoxide / 20 - 30 °C / Inert atmosphere
1.2: 3 h / 20 °C / Inert atmosphere
2.1: Nessler's reagent / ethanol; water / Cooling with ice
2.2: 4 h / 90 - 125 °C / Inert atmosphere
3.1: acetic acid / Reflux
4.1: Ni-P2/EDA
View Scheme
参考文献
Gansca, Lucia; Andreica, Adriana; Ciotlaus, Irina; Maxim, Sanda; Oprean, Ioan
Revue Roumaine de Chimie, 2011 , vol. 56, # 7 p. 705 - 709
反应条件
1: C32H41N3O4Ru / tetrahydrofuran / 5 h / 20 °C / |Inert atmosphere; |Glovebox
2: pyridine / dichloromethane / 12 h / 20 °C / |Inert atmosphere
View Scheme
参考文献
Herbert, Myles B.; Marx, Vanessa M.; Pederson, Richard L.; Grubbs, Robert H.
Angewandte Chemie - International Edition, 2013 , vol. 52, # 1 p. 310 - 314
Angew. Chem., 2012 , vol. 125, # 1 p. 328 - 332,5
反应条件
1: 71 percent / tetrahydrofuran / -79 °C
2: acetic acid / 80 °C
View Scheme
参考文献
Macdonald, Timothy L.; Narayanan, Amirthalingam B.; O'Dell, Dale E.
Journal of Organic Chemistry, 1981 , vol. 46, # 7 p. 1504 - 1506
反应条件
aluminium trichloride; iodine; palladium
1.) CH2Cl2, 0 gradC, 1h. 2.) THF; Multistep reaction;
参考文献
Chan, T. H.; Koumaglo, K.
Tetrahedron Letters, 1986 , vol. 27, # 8 p. 883 - 886
反应条件
1: 1) cuprous iodide, 2,2'-bipyridyl; 2) magnesium / 1) abs. THF, 2 deg C, 10 min; 2) abs. THF.
2: 1) water, p-toluenesulfonic acid; 2) pyridine / 1) methanol, room temp., 2) room temp.
View Scheme
参考文献
Odinokov, V. N.; Ishmuratov, G. Yu.; Galeeva, R. I.; Kharisov, R. Ya.; Sokol'skaya, O. V.; at al.
Journal of Organic Chemistry USSR (English Translation), 1988 , vol. 24, # 4 p. 646 - 651
Zhurnal Organicheskoi Khimii, 1988 , vol. 24, # 4 p. 719 - 724
反应条件
1: 1) coprous iodide, 2,2'-bipyridyl; 2) Mg / 1) abs. THF, 10 min; 2) abs. THF
2: 1) water, p-toluenesulfonic acid; 2) pyridine / 1) methanol, room temp., 2) room temp.
View Scheme
参考文献
Odinokov, V. N.; Ishmuratov, G. Yu.; Galeeva, R. I.; Kharisov, R. Ya.; Sokol'skaya, O. V.; at al.
Journal of Organic Chemistry USSR (English Translation), 1988 , vol. 24, # 4 p. 646 - 651
Zhurnal Organicheskoi Khimii, 1988 , vol. 24, # 4 p. 719 - 724
反应条件
1: 1) coprous iodide, 2,2'-bipyridyl; 2) Mg / 1) abs. THF, 10 min; 2) abs. THF
2: 1) water, p-toluenesulfonic acid; 2) pyridine / 1) methanol, room temp., 2) room temp.
View Scheme
参考文献
Odinokov, V. N.; Ishmuratov, G. Yu.; Galeeva, R. I.; Kharisov, R. Ya.; Sokol'skaya, O. V.; at al.
Journal of Organic Chemistry USSR (English Translation), 1988 , vol. 24, # 4 p. 646 - 651
Zhurnal Organicheskoi Khimii, 1988 , vol. 24, # 4 p. 719 - 724
反应条件
1: 83 percent
2: 1) LiNH2
3: 1) O3, 2) NaBH4 / 1) cyclohexane, MeOH
View Scheme
参考文献
Ishmuratov; Ishmuratova; Odinokov; Tolstikov
Chemistry of Natural Compounds, 1997 , vol. 33, # 1 p. 25 - 30
反应条件
1: 1) LiNH2
2: 1) O3, 2) NaBH4 / 1) cyclohexane, MeOH
View Scheme
参考文献
Ishmuratov; Ishmuratova; Odinokov; Tolstikov
Chemistry of Natural Compounds, 1997 , vol. 33, # 1 p. 25 - 30
