3-(4-硝基苯基)-1-丙醇合成路线 （共 17 条）
反应条件
sodium tetrahydroborate
T=20°C; 0.25 h;
参考文献
Dalla, Vincent; Decroix, Bernard
Tetrahedron Letters, 2002 , vol. 43, # 9 p. 1657 - 1660
反应条件
1: 38.9 percent / HNO3; H2SO4 / 0.5 h / 50 °C
2: 98 percent / NaI / acetone / 17 h / Heating
3: 52 percent / AgNO3 / H2O; dioxane / 2 h / 45 °C
View Scheme
参考文献
Blankespoor, Ronald L.; DeVries, Tim; Hansen, Eric; Kallemeyn, Jeffrey M.; Klooster, Aaron M.; Mulder, Jason A.; Smart, Robert P.; Vander Griend, Douglas A.
Journal of Organic Chemistry, 2002 , vol. 67, # 8 p. 2677 - 2681
反应条件
1: sulfuric acid / 1.5 h / Reflux
2: lithium borohydride; 1-n-decene / tetrahydrofuran / 18 h / 20 °C / Inert atmosphere
View Scheme
参考文献
Pinto, Orlando; Sardinha, Joao; Vaz, Pedro D.; Piedade, Fatima; Calhorda, Maria J.; Abramovitch, Rudolph; Nazareth, Nair; Pinto, Madalena; Nascimento, Maria S. J.; Rauter, Amelia P.
Journal of Medicinal Chemistry, 2011 , vol. 54, # 9 p. 3175 - 3187
反应条件
1: sodium hydride / tetrahydrofuran
2: sodium chloride / dimethyl sulfoxide
3: diisobutylaluminium hydride
View Scheme
参考文献
Jayasekara, P. Suresh; Barrett, Matthew O.; Ball, Christopher B.; Brown, Kyle A.; Hammes, Eva; Balasubramanian, Ramachandran; Harden, T. Kendall; Jacobson, Kenneth A.
Journal of Medicinal Chemistry, 2014 , vol. 57, # 9 p. 3874 - 3883
反应条件
diisobutylaluminium hydride
参考文献
Jayasekara, P. Suresh; Barrett, Matthew O.; Ball, Christopher B.; Brown, Kyle A.; Hammes, Eva; Balasubramanian, Ramachandran; Harden, T. Kendall; Jacobson, Kenneth A.
Journal of Medicinal Chemistry, 2014 , vol. 57, # 9 p. 3874 - 3883
反应条件
1: pyridine / CHCl3 / 16 h / Ambient temperature
2: NH3 / dioxane / 3 h / 90 - 100 °C
View Scheme
参考文献
Katakami; Yokoyama; Miyamoto; Mori; Kawauchi; Nobori; San-nohe; Kaiho; Kamiya
Journal of Medicinal Chemistry, 1992 , vol. 35, # 18 p. 3325 - 3330
反应条件
pyridinium chlorochromate in dichloromethane
1.5 h; Heating;
参考文献
Blankespoor, Ronald L.; DeVries, Tim; Hansen, Eric; Kallemeyn, Jeffrey M.; Klooster, Aaron M.; Mulder, Jason A.; Smart, Robert P.; Vander Griend, Douglas A.
Journal of Organic Chemistry, 2002 , vol. 67, # 8 p. 2677 - 2681
