1-(4-氯苯基)-5-甲基-1H-1,2,3-噻唑-4-羧酸合成路线 （共 5 条）
反应条件
1: With sodium ethanolate in ethanol Cycloaddition; 2: With sodium hydroxide in water Hydrolysis;
参考文献
Shen; Chen; Wu; Dong
Journal of Heterocyclic Chemistry, 2013 , vol. 50, # 4 p. 781 - 786
反应条件
1.1: NaNO2; aq. HCl / 0 - 5 °C 1.2: NaN3 2.1: EtONa / ethanol View Scheme
参考文献
Shen; Chen; Wu; Dong
Journal of Heterocyclic Chemistry, 2013 , vol. 50, # 4 p. 781 - 786
反应条件
1: With sodium methylate in methanol T=75 - 80°C; 2: With water; sodium hydroxide
参考文献
Pokhodylo; Matiychuk; Obushak
Chemistry of Heterocyclic Compounds, 2009 , vol. 45, # 12 p. 1469 - 1472
反应条件
1: sodium ethoxide / ethanol 2: sodium hydroxide / H2O View Scheme
参考文献
Sun, Xiao-Wen; Xu, Peng-Fei; Zhang, Zi-Yi
Magnetic Resonance in Chemistry, 1998 , vol. 36, # 6 p. 459 - 460
反应条件
thionyl chloride
4 h; Heating;
参考文献
Quan, Bin; Zhuang, Shan-Xue; Li, Chun-Cheng; Dong, Heng-Shan
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2005 , vol. 44, # 8 p. 1717 - 1719
