(i) BF3-Et2O, (ii) /BRN= 102415/, (iii) aq. NaOH, MeOH; Multistep reaction;

potassium; magnesium oxide T=309.85°C; 3 h; Product distribution; Further Variations:TemperaturesReagents;

暂无反应条件数据

1: Br2 / Fe / CH2Cl2 2: 0.83 g / 2,6-pyridinedicarboxylic acid; ammonium cerium(IV) nitrate / H2O; acetonitrile / 20 °C 3: 100 percent / CH2Cl2 / 40 h 4: NaOMe / toluene / 2 h / 0 - 20 °C 5: 96 percent / maleic anhydride / toluene / 4 h / Heating View Scheme

1: BF3-Et2O / methanol; ethyl acetate 2: (i) xylene, (ii) aq. NaOH, MeOH View Scheme

1.1: Br2 / Fe / CH2Cl2 2.1: 0.83 g / 2,6-pyridinedicarboxylic acid; ammonium cerium(IV) nitrate / H2O; acetonitrile / 20 °C 3.1: 100 percent / CH2Cl2 / 40 h 4.1: NaOMe / toluene / 2 h / 0 - 20 °C 5.1: 96 percent / maleic anhydride / toluene / 4 h / Heating 6.1: LDA; tributyltin hydride / tetrahydrofuran; hexane / 2 h 6.2: Ag2O / BF3*OEt2 / CH2Cl2 / 2 h View Scheme

暂无反应条件数据

1: Cs2CO3 / acetonitrile / 25 °C 2: NaBr; Br2 / methanol / 0 °C View Scheme

Fremy’s salt in phosphate buffer; diethyl ether 18 h;