2-氨基-4-甲氧基苯酚合成路线 （共 33 条）
反应条件
potassium hydroxide in methanol; water
参考文献
Yoshida, Satoshi; Watanabe, Takashi; Sato, Yasuo
Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 10 p. 3515 - 3523
反应条件
potassium carbonate in N,N-dimethyl-formamide T=125°C; 15 h;
参考文献
Mizar, Pushpak; Myrboh, Bekington
Tetrahedron Letters, 2006 , vol. 47, # 44 p. 7823 - 7826
反应条件
1: 87 percent / K2CO3 / acetonitrile / 2 h / Heating 2: 91 percent / LiAlH4 / tetrahydrofuran / 20 °C View Scheme
参考文献
Vermeulen, Erik S; van Smeden, Marjan; Schmidt, Anne W; Sprouse, Jeffrey S; Wikstroem, Hakan V; Grol, Cor J
Journal of medicinal chemistry, 2004 , vol. 47, # 22 p. 5451 - 5466
反应条件
NH4PF6; tri-ruthenium(0)dodecacarbonyl in methanol T=80°C; 48 h;
参考文献
Journal of the American Chemical Society, , vol. 125, # 22 p. 6646 - 6647
反应条件
in orthoacetic acid trimethyl ester; ethyl acetate
反应条件
in neat (no solvent) 0.333333 h; RefluxInert atmosphere;
参考文献
Journal of the American Chemical Society, , vol. 136, # 11 p. 4287 - 4299
参考文献
Yakugaku Zasshi, , vol. 65, p. Ausg. B, S. 532
Chem.Abstr., , p. 110
反应条件
potassium carbonate in acetonitrile 2 h; Heating;
参考文献
Vermeulen, Erik S; van Smeden, Marjan; Schmidt, Anne W; Sprouse, Jeffrey S; Wikstroem, Hakan V; Grol, Cor J
Journal of medicinal chemistry, 2004 , vol. 47, # 22 p. 5451 - 5466
反应条件
1: Et3N 2: aq. NaOH / ethanol / Heating View Scheme
参考文献
Drain; Daly; Davy; Horlington; Howes; Scruton; Selway
The Journal of pharmacy and pharmacology, 1970 , vol. 22, # 9 p. 684 - 693
反应条件
in 5-(Oxiran-2-yl-methoxy)-2-1(3-trifluoromethyl)phenyl]benzoxazole
参考文献
CV Therapeutics, Inc.
Patent: US6573264 B1, 2003 ;
