2-氨基-4,5-二氟苯甲酸甲酯合成路线 （共 4 条）
反应条件
hydrogen; palladium 10 on activated carbon in ethyl acetate P=2585.81 Torr; 3 h;
参考文献
PORTOLA PHARMACEUTICALS, INC.
Patent: WO2008/36843 A2, 2008 ;
Location in patent: Page/Page column 33 ;
WO 2008/036843 A2
反应条件
in methanol; hexanes; dichloromethane T=20°C; 0.5 h; Inert atmosphere;
参考文献
Wadell, Göran; Edlund, Karin; Strand, Marten; Andersson, Emma; Öberg, Christopher; Elofsson, Mikael; Mei, Ya-Fang
Patent: US2013/210915 A1, 2013 ;
Location in patent: Paragraph 0302 ;
反应条件
potassium carbonate in 1,4-dioxane; methanol; water
参考文献
Chemistry of Heterocyclic Compounds, , vol. 42, # 1 p. 64 - 69
