反应条件
1: 94 percent / PBr3, pyridine / diethyl ether / 3 h / -30 - 23 °C
2: 1.) EtMgBr, 2.) CuI / 1.) THF, 23 deg C, 12 h, 2.) THF, reflux, 18 h
3: 99 percent / Br2, 1,2-bis(diphenylphosphino)ethane / CH2Cl2 / 2 h / 23 °C
4: 1.) EtMgBr, 2.) CuI / 1.) THF, 23 deg C, 10 h, 2.) THF, 23 deg C, 2 h
5: 91 percent / H2 / 10percent Pd/BaSO4, quinoline / ethyl acetate / 0.75 h / 23 °C / 760 Torr
6: 93 percent / Br2, 1,2-bis(diphenylphosphino)ethane / CH2Cl2 / 9 h / 23 °C
View Scheme
参考文献
Kerdesky; Holms; Schmidt et al.
Tetrahedron Letters, 1985 , vol. 26, # 18 p. 2143 - 2146
