反应条件
1: 77 percent / PBr3, pyridine / diethyl ether / 1.) -15 deg C, 2 h, 2.) room temp., 3 h, then 30 deg C, 45 min
2: 1.) Mg / 1.) Et2O, 2.) Et2O, -15 deg C, 0.5 h, -15 to 0 deg C, 0.5 h
3: 68 percent / propionic acid / 2 h / 136 - 139 °C
4: 90 percent / NaB4, aq. NaOH, Ni(OAr)2*4H2O, ethylenediamine, H2 / ethanol / Ambient temperature
5: 89 percent / LiAlH4 / diethyl ether / 2 h / 0 °C
6: 80 percent / pyridine / 12 h / Ambient temperature
View Scheme
参考文献
Nishiyama, Hisao; Sakuta, Koji; Itoh, Kenji
Tetrahedron Letters, 1984 , vol. 25, # 2 p. 223 - 226
