反应条件
1: 4-bromo(1H)-pyrazole; 1-bromo-2-chloro-ethane With caesium carbonate in N,N-dimethyl-formamide
T=60°C; 1 h; Microwave irradiation;
2: dimethyl amine in tetrahydrofuran; N,N-dimethyl-formamide
T=60 - 100°C; Microwave irradiation;
参考文献
Demont, Emmanuel Hubert; Garton, Neil Stuart; Gosmini, Romain Luc Marie; Hayhow, Thomas George Christopher; Seal, Jonathan; Wilson, David Matthew; Woodrow, Michael David
Patent: US2012/208798 A1, 2012 ;
Location in patent: Page/Page column 19 ;