(2S,3R,4E)-2-氨基-3-羟基-4-十八碳烯-1-基二[1-(2-硝基苯基)乙基]磷酸酯合成路线 (共 8 条)
反应条件
trifluoroacetic acid in dichloromethane
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 8, # 7 p. 711 - 714
反应条件
1: 62 percent / Et3N / tetrahydrofuran / -78 - 0 °C 2: tetrazole / acetonitrile 3: I2, pyridine, water / CH2Cl2 4: 56 percent / TFA / CH2Cl2 View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 8, # 7 p. 711 - 714
反应条件
1: 55 percent / DMAP / CH2Cl2 2: p-TsOH / benzene / Heating 3: NaOMe, MeOH 4: tetrazole / acetonitrile 5: I2, pyridine, water / CH2Cl2 6: 56 percent / TFA / CH2Cl2 View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 8, # 7 p. 711 - 714
反应条件
1: tetrazole / acetonitrile 2: I2, pyridine, water / CH2Cl2 3: 56 percent / TFA / CH2Cl2 View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 8, # 7 p. 711 - 714
反应条件
1: tetrazole / acetonitrile 2: I2, pyridine, water / CH2Cl2 3: 56 percent / TFA / CH2Cl2 View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 8, # 7 p. 711 - 714
反应条件
1: p-TsOH / benzene / Heating 2: NaOMe, MeOH 3: tetrazole / acetonitrile 4: I2, pyridine, water / CH2Cl2 5: 56 percent / TFA / CH2Cl2 View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 8, # 7 p. 711 - 714
反应条件
in chloroform-d1 48 h; Irradiation;
参考文献
Qiao, Lixin; Kozikowski, Alan P.; Olivera, Ana; Spiegel, Sarah
Bioorganic and Medicinal Chemistry Letters, 1998 , vol. 8, # 7 p. 711 - 714
反应条件
in chloroform-d1
48 h; Irradiation;
参考文献
Qiao, Lixin; Kozikowski, Alan P.; Olivera, Ana; Spiegel, Sarah
Bioorganic and Medicinal Chemistry Letters, 1998 , vol. 8, # 7 p. 711 - 714