二[1-(2-硝基苯基)乙基]N,N-二异丙基亚磷酰胺合成路线 （共 4 条）
反应条件
triethylamine in tetrahydrofuran T=-20 - 20°C; Condensation;
参考文献
Scheigetz, John; Roy, Bruno
Synthetic Communications, 2000 , vol. 30, # 8 p. 1437 - 1445
反应条件
1: 89 percent / DIBAL-H / tetrahydrofuran; toluene / 0.25 h / 0 °C 2: 80 percent / Et3N / tetrahydrofuran / -20 - 20 °C View Scheme
参考文献
Synthetic Communications, , vol. 30, # 8 p. 1437 - 1445
反应条件
1: tetrazole / acetonitrile 2: I2, pyridine, water / CH2Cl2 3: 56 percent / TFA / CH2Cl2 View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 8, # 7 p. 711 - 714
反应条件
1: tetrazole / acetonitrile
2: I2, pyridine, water / CH2Cl2
3: 56 percent / TFA / CH2Cl2
4: CDCl3 / 48 h / Irradiation
View Scheme
参考文献
Qiao, Lixin; Kozikowski, Alan P.; Olivera, Ana; Spiegel, Sarah
Bioorganic and Medicinal Chemistry Letters, 1998 , vol. 8, # 7 p. 711 - 714
