1-Boc-4-(1-吡咯烷)-3,6-二氢-2H-吡啶合成路线

参考文献

SMITHKLINE BEECHAM CORPORATION
Patent: WO2009/56556 A1, 2009 ;
Location in patent: Page/Page column 43 ;
WO 2009/056556 A1

420-04-2单氰胺+

207691-65-41-Boc-4-(1-吡咯烷)-3,6-二氢-2H-吡啶

365996-05-02-氨基-6,7-二氢噻唑并[5,4-c]吡啶-5(4H)-甲酸叔丁酯

参考文献

DAIICHI PHARMACEUTICAL CO., LTD.
Patent: EP1405852 A1, 2004 ;
Location in patent: Page 65 ;
EP 1405852 A1

207691-65-41-Boc-4-(1-吡咯烷)-3,6-二氢-2H-吡啶

1165923-89-66-羟基-5-甲基-3,4-二氢异喹啉-2(1h)-羧酸叔丁酯

参考文献

Demont, Emmanuel H.; Andrews, Benjamin I.; Bit, Rino A.; Campbell, Colin A.; Cooke, Jason W. B.; Deeks, Nigel; Desai, Sapna; Dowell, Simon J.; Gaskin, Pam; Gray, James R. J.; Haynes, Andrea; Holmes, Duncan S.; Kumar, Umesh; Morse, Mary A.; Osborne, Greg J.; Panchal, Terry; Patel, Bela; Perboni, Alcide; Taylor, Simon; Watson, Robert; Witherington, Jason; Willis, Robert
ACS Medicinal Chemistry Letters, 2011 , vol. 2, # 6 p. 444 - 449

207691-65-41-Boc-4-(1-吡咯烷)-3,6-二氢-2H-吡啶

1165923-92-16-氰基-5-甲基-3,4-二氢异喹啉-2(1h)-羧酸叔丁酯

参考文献

Demont, Emmanuel H.; Andrews, Benjamin I.; Bit, Rino A.; Campbell, Colin A.; Cooke, Jason W. B.; Deeks, Nigel; Desai, Sapna; Dowell, Simon J.; Gaskin, Pam; Gray, James R. J.; Haynes, Andrea; Holmes, Duncan S.; Kumar, Umesh; Morse, Mary A.; Osborne, Greg J.; Panchal, Terry; Patel, Bela; Perboni, Alcide; Taylor, Simon; Watson, Robert; Witherington, Jason; Willis, Robert
ACS Medicinal Chemistry Letters, 2011 , vol. 2, # 6 p. 444 - 449

814-68-6丙烯酰氯+

207691-65-41-Boc-4-(1-吡咯烷)-3,6-二氢-2H-吡啶

402476-94-2

参考文献

Williams, Brian D.; Williams, Birute; Bernardoni, Francis; Finn, Robert C.; Zubieta, Jon
Heterocycles, 2001 , vol. 55, # 11 p. 2199 - 2206