1-(boc-氨基)-3-环戊烯羧酸乙酯合成路线 （共 10 条）
反应条件
sodium hydroxide in ethanol; water Heating;
参考文献
Park, Kyung-Ho; Olmstead, Marilyn M.; Kurth, Mark J.
Synlett, 2003 , # 9 SPEC. ISS. p. 1267 - 1270
反应条件
in dichloromethane
Heating;
参考文献
Park, Kyung-Ho; Olmstead, Marilyn M.; Kurth, Mark J.
Journal of Organic Chemistry, 1998 , vol. 63, # 19 p. 6579 - 6585
Title/Abstract Full Text View citing articles Show Details
Park, Kyung-Ho; Olmstead, Marilyn M.; Kurth, Mark J.
Synlett, 2003 , # 9 SPEC. ISS. p. 1267 - 1270
反应条件
1.1: n-BuLi / tetrahydrofuran; hexane / 1 h / -78 °C
1.2: 76 percent / tetrahydrofuran; hexane / 16 h / -78 - 20 °C
2.1: 63 percent / Grubbs second generation catalyst / CH2Cl2 / 0.25 h / 140 °C / microwave irradiation
3.1: TFA; water / acetonitrile / 0.33 h / 60 °C / microwave irradiation
4.1: 0.56 g / tetrahydrofuran / 20 h / Heating
View Scheme
参考文献
Jam, Fariba; Tullberg, Marcus; Luthman, Kristina; Grotli, Morten
Tetrahedron, 2007 , vol. 63, # 39 p. 9881 - 9889
反应条件
1: 63 percent / Grubbs second generation catalyst / CH2Cl2 / 0.25 h / 140 °C / microwave irradiation
2: TFA; water / acetonitrile / 0.33 h / 60 °C / microwave irradiation
3: 0.56 g / tetrahydrofuran / 20 h / Heating
View Scheme
参考文献
Jam, Fariba; Tullberg, Marcus; Luthman, Kristina; Grotli, Morten
Tetrahedron, 2007 , vol. 63, # 39 p. 9881 - 9889
反应条件
1.1: hydrogenchloride; water / Inert atmosphere
1.2: Inert atmosphere
2.1: sodium hydrogencarbonate / water / Inert atmosphere
View Scheme
参考文献
Kim, Simon; Ciufolini, Marco A.
Organic Letters, 2011 , vol. 13, # 12 p. 3274 - 3277
反应条件
1: NaN3 / acetone; H2O / 0.5 h / 3 - 6 °C
2: 3 Angstroem MS / 2-methyl-propan-2-ol / 2 h / Heating
3: 16.1 g / SnCl4 / 1 h / Heating
View Scheme
参考文献
Hodgson, David M.; Thompson, Alison J.; Wadman, Sjoerd; Keats, Clare J.
Tetrahedron, 1999 , vol. 55, # 35 p. 10815 - 10834
反应条件
1: TFA; water / acetonitrile / 0.33 h / 60 °C / microwave irradiation
2: 0.56 g / tetrahydrofuran / 20 h / Heating
View Scheme
参考文献
Jam, Fariba; Tullberg, Marcus; Luthman, Kristina; Grotli, Morten
Tetrahedron, 2007 , vol. 63, # 39 p. 9881 - 9889
反应条件
1: (COCl)2; DMF / CH2Cl2 / 100 °C
2: NaN3 / acetone; H2O / 0.5 h / 3 - 6 °C
3: 3 Angstroem MS / 2-methyl-propan-2-ol / 2 h / Heating
4: 16.1 g / SnCl4 / 1 h / Heating
View Scheme
参考文献
Hodgson, David M.; Thompson, Alison J.; Wadman, Sjoerd; Keats, Clare J.
Tetrahedron, 1999 , vol. 55, # 35 p. 10815 - 10834
反应条件
4 A molecular sieve; tin(IV) chloride in toluene
3 h; Heating; Yield given;
参考文献
Hodgson, David M.; Thompson, Alison J.; Wadman, Sjoerd
Tetrahedron Letters, 1998 , vol. 39, # 20 p. 3357 - 3358
反应条件
tin(IV) chloride
Addition; 1 h; Heating;
参考文献
Hodgson, David M.; Thompson, Alison J.; Wadman, Sjoerd; Keats, Clare J.
Tetrahedron, 1999 , vol. 55, # 35 p. 10815 - 10834
