2-甲氧基-吡啶 1-氧化物合成路线 （共 18 条）
反应条件
sulfuric acid; nitric acid T=75°C; 1.5 h;
参考文献
Webber; Bleckman; Attard; Deal; Kathardekar; Welsh; Janson; Matthews; Smith; Freer; Jordan; Bacquet; Howland; Booth; Ward; Hermann; White; Morse; et al.
Journal of Medicinal Chemistry, 1993 , vol. 36, # 6 p. 733 - 746
反应条件
triethylamine in acetonitrile Heating;
参考文献
Sakamoto, Takao; Kaneda, Soh-ichi; Nishimura, Sumiko; Yamanaka, Hiroshi
Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 2 p. 565 - 571
反应条件
sulfuric acid; nitric acid T=75°C; 1.5 h;
参考文献
Journal of Medicinal Chemistry, , vol. 36, # 6 p. 733 - 746
反应条件
1: 48 percent / HNO3; H2SO4 / 100 °C 2: 98 percent / Fe; AcOH / 100 °C 3: 43 percent / NaNO2; NaBr; CuSO4 / H2SO4 / 0 °C View Scheme
参考文献
RESEARCH TRIANGLE INSTITUTE; CARROLL, Frank Ivy; ONDACHI, Pauline Wanjiku
Patent: WO2012/24615 A1, 2012 ;
WO 2012/024615 A1
反应条件
hydrogenchloride; water T=90 - 100°C; 16 h;
参考文献
Chemistry - A European Journal, , vol. 4, # 5 p. 886 - 902
反应条件
1: 48 percent / HNO3; H2SO4 / 100 °C 2: 98 percent / Fe; AcOH / 100 °C View Scheme
参考文献
RESEARCH TRIANGLE INSTITUTE; CARROLL, Frank Ivy; ONDACHI, Pauline Wanjiku
Patent: WO2012/24615 A1, 2012 ;
WO 2012/024615 A1
反应条件
chloro-trimethyl-silane; sodium iodide; zinc in acetonitrile T=55 - 60°C; 1 h;
参考文献
Morita, Tsuyoshi; Kuroda, Koji; Okamoto, Yoshiki; Sakurai, Hiroshi
Chemistry Letters, 1981 , p. 921 - 924
反应条件
in chloroform-d1
20 h; Heating;
参考文献
Wolfe, Saul; Yang, Kiyull; Weinberg, Noham; Shi, Zheng; Hsieh, Yih-Huang; Sharma, Rajendra Dev; Ro, Stephen; Kim, Chan-Kyung
Chemistry - A European Journal, 1998 , vol. 4, # 5 p. 886 - 902
