2-氨基-4,6-二氯苯甲酸合成路线 (共 3 条)
反应条件
sodium hydroxide; dihydrogen peroxide in water 2 h;
参考文献
KOREA RESERACH INSTITUTE OF CHEMICAL TECHNOLOGY
Patent: WO2008/4716 A1, 2008 ;
Location in patent: Page/Page column 25-26 ;
WO 2008/004716 A1
反应条件
1: With 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride in tetrahydrofuran T=20°C; 0.333333 h; 2: With ammonium hydroxide in water T=20°C; 20 h;
参考文献
RVX Therapeutics Inc.; McLure, Kevin G.; Young, Peter R.
Patent: US2013/281399 A1, 2013 ;
Location in patent: Paragraph 0620 ;
反应条件
tert.-butylnitrite; copper(ll) bromide in acetonitrile
T=0 - 20°C;
参考文献
SANOFI-AVENTIS
Patent: US2009/215728 A1, 2009 ;
Location in patent: Page/Page column 44 ;
US 20090215728 A1