2-氨基-5-氯-3-甲基苯甲酸合成路线 （共 12 条）
反应条件
1: With 1,8-diazabicyclo[5.4.0]undec-7-ene in acetonitrile
T=0 - 5°C; 8 h;
2: With hydrogenchloride in acetonitrile
T=0 - 10°C; 0.5 h; Product distribution / selectivity;
参考文献
E.I. DUPONT DE NEMOURS AND COMPANY
Patent: WO2006/62978 A1, 2006 ;
Location in patent: Page/Page column 22 ;
反应条件
1: thionyl chloride / 3 h / |Reflux
2: tetrahydrofuran / 20 °C / |Cooling with ice
View Scheme
参考文献
Zhao, Yu; Li, Yongqiang; Xiong, Lixia; Wang, Hongxue; Li, Zhengming
Chinese Journal of Chemistry, 2012 , vol. 30, # 8 p. 1748 - 1758
