5-溴烟酸合成路线

20826-04-45-溴烟酸

13535-01-85-溴-3-氨基吡啶

参考文献

ChemMedChem, , vol. 9, # 1 p. 217 - 232

20826-04-45-溴烟酸+

87199-15-33-羟甲基苯硼酸

1261974-04-2

参考文献

Journal of Medicinal Chemistry, , vol. 53, # 16 p. 6129 - 6152

20826-04-45-溴烟酸+

64-17-5乙醇

20986-40-75-溴烟酸乙酯

参考文献

THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Patent: WO2008/151073 A1, 2008 ;
Location in patent: Page/Page column 39-40; 44 ;

20826-04-45-溴烟酸

20986-40-75-溴烟酸乙酯

参考文献

Bachman; Micucci
Journal of the American Chemical Society, 1948 , vol. 70, p. 2381,2383
Full Text Show Details
Dukat, Malgorzata; Ramunno, Anna; Banzi, Rita; Damaj, M. Imad; Martin, Billy; Glennon, Richard A.
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 19 p. 4308 - 4312

20826-04-45-溴烟酸+

7664-93-9硫酸

20986-40-75-溴烟酸乙酯

参考文献

Duphar International Research B.V.
Patent: US6090812 A1, 2000 ;
US 6090812 A

20826-04-45-溴烟酸+

24424-99-5二碳酸二叔丁酯

263270-02-65-溴烟酸叔丁酯

参考文献

Wright, Stephen W.
Journal of Heterocyclic Chemistry, 2012 , vol. 49, # 2 p. 442 - 445

20826-04-45-溴烟酸+

75-65-0叔丁醇

263270-02-65-溴烟酸叔丁酯

参考文献

MERCK and CO., INC.; BANYU PHARMACEUTICAL CO., LTD.
Patent: WO2008/88692 A2, 2008 ;
Location in patent: Page/Page column 105 ;

20826-04-45-溴烟酸+

67098-46-8

263270-02-65-溴烟酸叔丁酯

参考文献

Tanaka, Taisaku; Sugawara, Hajime; Maruoka, Hiroshi; Imajo, Seiichi; Muto, Tsuyoshi
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 14 p. 4233 - 4249

20826-04-45-溴烟酸+

75-04-7乙胺

173999-48-95-溴-N-乙基烟酰胺

参考文献

PFIZER INC.,
Patent: WO2006/54151 A1, 2006 ;
Location in patent: Page/Page column 10 ;

20826-04-45-溴烟酸+

1117-97-1N-甲基-N-甲氧基胺盐酸盐

183608-47-15-溴-n-甲氧基-n-甲基烟酰胺

参考文献

F. HOFFMANN-LA ROCHE AG; AEBI, Johannes; AMREIN, Kurt; HORNSPERGER, Benoit; KNUST, Henner; KUHN, Bernd; LIU, Yongfu; MAERKI, Hans P.; MAYWEG, Alexander V.; MOHR, Peter; TAN, Xuefei; ZHOU, Mingwei
Patent: WO2013/37779 A1, 2013 ;
Location in patent: Page/Page column 235 ;