1: 82 percent / Bu4NF / acetonitrile / 48 h / Heating 2: 94 percent / H2 / PtO2 / ethanol / 24 h / 20 °C 3: 79 percent / CF3COOH / methanol / 0.5 h / 20 °C 4: 80 percent / pyridine / 144 h / -28 °C 5: 90 percent / LiAlH4 / tetrahydrofuran / 4 h / Heating 6: 80 percent / pyridine / 48 h / 20 °C 7: 66 percent / dimethylformamide / 24 h / 100 °C 8: 0.7 g / trifluoroacetic acid; aq. HCl / 24 h / 4 °C 9: NaBH4 / methanol / 2 h / 20 °C 10: 84 percent / imidazole; Ph3P; iodine / toluene / 3 h / Heating 11: 83 percent / K2CO3 / methanol; tetrahydrofuran / 1.5 h / 20 °C 12: 93 percent / ethanol / 3 h / 80 °C View Scheme

<b>Multi-step reaction with 3 steps<br /> </b>1: 26.2 g / pyridine / 240 h / 20 &deg;C<br />2: 6.65 g / toluene-4-sulfonic acid / 5 h / 80 &deg;C<br />3: 77 percent / toluene-4-sulfonic acid / 24 h / 20 &deg;C<br /> <br /> &nbsp;