2,5-双(三氟甲基)吡啶合成路线 （共 4 条）
反应条件
in N,N-dimethyl-formamide T=80°C; 8 h; Sealed tubeInert atmosphere; regioselective reaction;
参考文献
Mormino, Michael G.; Fier, Patrick S.; Hartwig, John F.
Organic Letters, 2014 , vol. 16, # 6 p. 1744 - 1747
反应条件
1-methyl-pyrrolidin-2-one; copper(l) iodide T=160°C; 4 h;
参考文献
Carr, Gillian E.; Chambers, Richard D.; Holmes, Thomas F.; Parker, David G.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1988 , p. 921 - 926
反应条件
1-methyl-pyrrolidin-2-one; copper(l) iodide T=160°C; 4 h;
参考文献
Carr, Gillian E.; Chambers, Richard D.; Holmes, Thomas F.; Parker, David G.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1988 , p. 921 - 926
反应条件
1: 85 percent Chromat. / copper(I) iodide, N-methylpyrrolidin-2-one / 4 h / 160 °C 2: 27 percent Chromat. / copper(I) iodide, N-methylpyrrolidin-2-one / 4 h / 160 °C View Scheme
参考文献
Carr, Gillian E.; Chambers, Richard D.; Holmes, Thomas F.; Parker, David G.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1988 , p. 921 - 926
