2-氨基-N-(4-甲氧基苯基)-苯甲酰胺合成路线 （共 14 条）
反应条件
hydrogen; palladium 10 on activated carbon in methanol T=20°C; 16 h;
参考文献
XENON PHARMACEUTICALS INC.
Patent: WO2008/94909 A2, 2008 ;
Location in patent: Page/Page column 91 ;
WO 2008/094909 A2
反应条件
in ethyl acetate T=90°C; 2.5 h; Microwave irradiation;
参考文献
Cabrera-Rivera, Fanny A.; Ortiz-Nava, Claudia; Roman-Bravo, Perla; Escalante, Jaime; Leyva, Marco A.
Heterocycles, 2012 , vol. 85, # 9 p. 2173 - 2195,23
反应条件
1: 4-methoxy-aniline With trimethylaluminum in dichloromethane; toluene T=20°C; 45 h; 2: 2-amino-benzoic acid methyl ester in dichloromethane; toluene Heating;
参考文献
Correa, Arkaitz; Tellitu, Imanol; Dominguez, Esther; SanMartin, Raul
Journal of Organic Chemistry, 2006 , vol. 71, # 9 p. 3501 - 3505
反应条件
1: pyridine / CH2Cl2 / 20 °C 2: H2 / Raney Ni / tetrahydrofuran; ethyl acetate / 16 h / 20 °C / 3075.31 Torr View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 17 p. 4832 - 4836
反应条件
1: pyridine / CH2Cl2 / 20 °C 2: H2 / Raney Ni / tetrahydrofuran; ethyl acetate / 16 h / 20 °C / 3075.31 Torr View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 17 p. 4832 - 4836
反应条件
in diethyl ether T=0 - 10°C; 0.5 h;
参考文献
Mahiwal, Kuldeep; Kumar, Pradeep; Narasimhan, Balasubramanian
Medicinal Chemistry Research, 2012 , vol. 21, # 3 p. 293 - 307
反应条件
1: diluted hydrochloric acid 2: 125 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 9, p. 55,61, 63
反应条件
potassium alum in ethanol 4 h; Reflux;
参考文献
Tetrahedron, , vol. 65, # 18 p. 3804 - 3808
反应条件
iodine T=80°C; 0.5 h; Ionic liquid;
参考文献
Synthetic Communications, , vol. 42, # 3 p. 341 - 349
反应条件
1: ethanolic NaOH 2: acetone; KMnO4 View Scheme
参考文献
Feldman; Wagner
Journal of Organic Chemistry, 1942 , vol. 7, p. 31,42
