tetrabutyl ammonium fluoride in dimethyl sulfoxide T=25°C; 0.166667 h; Inert atmosphereMicrowave irradiationAnhydrous conditions;

iodine; fluorine; triethylamine in 1,2,2-trifluoro-trichloroethane T=0°C;

1: 83 percent / LiBF4, 20 percentF2/N2 / acetonitrile / -40 °C 2: 72 percent Chromat. / Et3N / 0.08 h / Ambient temperature View Scheme

fluorine T=0°C;

triethylamine 0.0833333 h; Ambient temperature;

1: 2-chloro-6-fluoropyridine With n-butyllithium; diisopropylamine in tetrahydrofuran; hexane T=-78°C; 1 h; Inert atmosphere; 2: N,N-dimethyl-formamide in tetrahydrofuran; hexane 1 h; Inert atmosphere; 3: With hydrogenchloride in tetrahydrofuran; diethyl ether; hexane T=-78°C; pH=1; Inert atmosphere;

hydrazine hydrate in ethanol T=55°C; 72 h;

1: With n-butyllithium; diisopropylamine in tetrahydrofuran; hexane T=-78 - 60°C; 1 h; 2: With tri-isopropoxy-borane in tetrahydrofuran; hexane T=-60 - 20°C; 3: With dihydrogen peroxide; sodium hydroxide in tetrahydrofuran; water