(5-硝基噻吩-2-基)甲醇合成路线 （共 12 条）
反应条件
silica-supported Jones reagent in dichloromethane 0.00269444 h;
参考文献
Wiles, Charlotte; Watts, Paul; Haswell, Stephen J.
Tetrahedron Letters, 2006 , vol. 47, # 30 p. 5261 - 5264
参考文献
Carella, Antonio; Castaldo, Anna; Centore, Roberto; Fort, Alain; Sirigu, Augusto; Tuzi, Angela
Journal of the Chemical Society. Perkin Transactions 2, 2002 , # 11 p. 1791 - 1795
反应条件
silica-supported Jones reagent in dichloromethane 0.035 h;
参考文献
Wiles, Charlotte; Watts, Paul; Haswell, Stephen J.
Tetrahedron Letters, 2006 , vol. 47, # 30 p. 5261 - 5264
反应条件
triphenylphosphine in dichloromethane
参考文献
Glaxo Wellcome Inc.
Patent: US5874472 A1, 1999 ;
参考文献
Takeda Chemical Industries, Ltd.
Patent: US5716944 A1, 1998 ;
反应条件
phosphorus tribromide in dichloromethane T=0 - 30°C; 5 h;
参考文献
Li, Zhao; Gao, Xinghui; Shi, Wen; Li, Xiaohua; Ma, Huimin
Chemical Communications, 2013 , vol. 49, # 52 p. 5859 - 5861
反应条件
sodium tetrahydroborate in ethanol
5 h;
参考文献
Wiles, Charlotte; Watts, Paul; Haswell, Stephen J.
Tetrahedron Letters, 2006 , vol. 47, # 30 p. 5261 - 5264
反应条件
tin(ll) chloride in methanol
T=40°C; Title compound not separated from byproducts;
参考文献
Ferrer, Sandra; Naughton, Declan P.; Threadgill, Michael D.
Tetrahedron, 2003 , vol. 59, # 19 p. 3437 - 3444
反应条件
1: With nitric acid in acetic anhydride
T=-20 - 20°C;
2: With sulfuric acid
1.25 h; Heating;
参考文献
Buehler, Sigrid; Lagoja, Irene; Giegrich, Heiner; Stengele, Klaus-Peter; Pfleiderer, Wolfgang
Helvetica Chimica Acta, 2004 , vol. 87, # 3 p. 620 - 659
反应条件
1: 98 percent / dicyclohexylcarbodiimide / ethyl acetate / 21 h
2: 75 percent / 4-dimethylaminopyridine / dimethylformamide / 48 h / 20 °C
3: SnCl2 / methanol / 40 °C
View Scheme
参考文献
Ferrer, Sandra; Naughton, Declan P.; Threadgill, Michael D.
Tetrahedron, 2003 , vol. 59, # 19 p. 3437 - 3444
