3-(2-氯吩噻嗪-10-基)丙-1-胺盐酸盐合成路线 （共 6 条）
反应条件
hydrazine hydrate in methanol T=20°C; 3 h;
参考文献
Motohashi, Noboru; Kawase, Masami; Molnar, Joseph; Ferenczy, Lajos; Wesolowska, Olga; Hendrich, Andrzej B.; Bobrowska-Haegerstrand, Malgorzata; Haegerstrand, Henry; Michalak, Krystyna
Arzneimittel-Forschung/Drug Research, 2003 , vol. 53, # 8 p. 590 - 599
反应条件
ethanol; ammonia; nickel T=100 - 110°C; P=66195.7 Torr; Hydrogenation;
参考文献
Godefroi; Wittle
Journal of Organic Chemistry, 1956 , vol. 21, p. 1163,1168
Full Text Show Details
Soc. Usines Chim. Rhone-Poulenc
Patent: DE1012915 , 1957 ;
反应条件
1: hydroquinone; tri-N-methyl-anilinium hydroxide 2: Raney nickel; NH3; ethanol / 100 - 110 °C / 66195.7 Torr / Hydrogenation View Scheme
参考文献
Fujii
Yakugaku Zasshi, 1956 , vol. 76, p. 644,647, 648
Chem.Abstr., 1957 , p. 425
反应条件
nickel; dimethyl amine; benzene T=110 - 116°C; P=58840.6 Torr; Hydrogenation;
参考文献
Fujii
Yakugaku Zasshi, 1956 , vol. 76, p. 644,647, 648
Chem.Abstr., 1957 , p. 425
参考文献
Soc. Usines Chim. Rhone-Poulenc
Patent: DE1012915 , 1957 ;
反应条件
1: iodine; sulfur 2: hydroquinone; tri-N-methyl-anilinium hydroxide 3: Raney nickel; NH3; ethanol / 100 - 110 °C / 66195.7 Torr / Hydrogenation View Scheme
参考文献
Sawizkaja et al.
Zhurnal Obshchei Khimii, 1956 , vol. 26, p. 2900,2903; engl. Ausg. S. 3227, 3229
