1,3-二甲基-8-硝基-1H-嘌呤2,6(3H,9H)-二酮合成路线 （共 17 条）
反应条件
1: 90 percent / potassium carbonate / dimethylformamide / 80 °C
2: 53 percent / concd. HCl / Heating
3: 65 percent / benzylamine / H2O / 8 h / 60 °C
View Scheme
参考文献
Mosselhi, Mosselhi A. N.; Abbass, Ikhlass M.
Bulletin of the Polish Academy of Sciences, Chemistry, 1993 , vol. 41, # 3 p. 179 - 186
反应条件
potassium carbonate in N,N-dimethyl-formamide
T=80°C;
参考文献
Mosselhi, Mosselhi A. N.; Abbass, Ikhlass M.
Bulletin of the Polish Academy of Sciences, Chemistry, 1993 , vol. 41, # 3 p. 179 - 186
反应条件
potassium carbonate in N,N-dimethyl-formamide
1.) 80 deg C, 30 min, 2.) RT;
参考文献
Mosselhi; Pfleiderer
Journal of Heterocyclic Chemistry, 1993 , vol. 30, # 5 p. 1221 - 1228
反应条件
1: 90 percent / potassium carbonate / dimethylformamide / 80 °C
2: 53 percent / concd. HCl / Heating
View Scheme
参考文献
Mosselhi, Mosselhi A. N.; Abbass, Ikhlass M.
Bulletin of the Polish Academy of Sciences, Chemistry, 1993 , vol. 41, # 3 p. 179 - 186
反应条件
in toluene
4 h; Heating;
参考文献
Yizun, Jin; Adams, Gerald E.; Parrick, John; Stratford, Ian J.
European Journal of Medicinal Chemistry, 1989 , vol. 24, p. 511 - 516
反应条件
1: 90 percent / potassium carbonate / dimethylformamide / 80 °C
2: 40 percent / sodium dithionite, water / 90 °C
View Scheme
参考文献
Mosselhi, Mosselhi A. N.; Abbass, Ikhlass M.
Bulletin of the Polish Academy of Sciences, Chemistry, 1993 , vol. 41, # 3 p. 179 - 186
反应条件
1: 85 percent / potassium carbonate / dimethylformamide / 80 °C
2: 59 percent / sodium dithionite, water / 90 °C
View Scheme
参考文献
Mosselhi, Mosselhi A. N.; Abbass, Ikhlass M.
Bulletin of the Polish Academy of Sciences, Chemistry, 1993 , vol. 41, # 3 p. 179 - 186
