N-叔丁基-4-氨基苯磺酰胺合成路线 （共 4 条）
反应条件
potassium hydroxide in methanol T=100°C; 4 h;
参考文献
J. Uriach and Cia. S.A.
Patent: EP1424329 A1, 2004 ;
Location in patent: Page 9 ;
反应条件
hydrogen; palladium 10 on activated carbon in ethanol 48 h;
参考文献
J. Uriach and Cia. S.A.
Patent: EP1424329 A1, 2004 ;
Location in patent: Page 8 ;
反应条件
1: 70 percent / 1,2-dimethoxy-ethane / 5 h / Heating 2: 89 percent / aq. KOH / methanol / 4 h / 100 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 46, # 16 p. 3463 - 3475
反应条件
1: 100 percent / toluene / 24 h / 110 °C 2: 87 percent / K2CO3 / methanol; 1,2-dimethoxy-ethane / 3 h / Heating 3: 82 percent / N-chlorosuccinimide / acetonitrile / 24 h / 81 °C 4: 84 percent / aq. HCl / 3 h / Heating View Scheme
参考文献
Almansa, Carmen; Alfon, Jose; De Arriba, Alberto F.; Cavalcanti, Fernando L.; Escamilla, Ignasi; Gomez, Luis A.; Miralles, Agusti; Soliva, Robert; Bartroli, Javier; Carceller, Elena; Merlos, Manuel; Garcia-Rafanell, Julian
Journal of Medicinal Chemistry, 2003 , vol. 46, # 16 p. 3463 - 3475
