(S)-1-苄基-哌啶-2-羧酸合成路线 （共 7 条）
反应条件
1: With potassium hydroxide in isopropyl alcohol T=40°C; 8 h; Inert atmosphere; 2: With hydrogenchloride in water; isopropyl alcohol pH=5 - 6;
参考文献
Alvarez-Ibarra, Carlos; Lujan, Juan F. Collados; Quiroga-Feijoo, Maria L.
Tetrahedron Asymmetry, 2010 , vol. 21, # 19 p. 2334 - 2345
反应条件
1: 98 percent / pyridine / CH2Cl2 / 0.25 h / 0 °C 2: CH2Cl2 / 24 h / -65 °C 3: Et3N / CH2Cl2 / 24 h / Ambient temperature 4: HCl gas / 24 h / 0 °C 5: 0.5 N aq. HCl / ethanol / 48 h / 0 °C 6: 6 N aq. HCl / 10 h / Heating View Scheme
参考文献
Nazabadioko, Serge; Perez, Ramon J.; Brieva, Rosario; Gotor, Vicente
Tetrahedron Asymmetry, 1998 , vol. 9, # 9 p. 1597 - 1604
反应条件
1: CH2Cl2 / 24 h / -65 °C 2: Et3N / CH2Cl2 / 24 h / Ambient temperature 3: HCl gas / 24 h / 0 °C 4: 0.5 N aq. HCl / ethanol / 48 h / 0 °C 5: 6 N aq. HCl / 10 h / Heating View Scheme
参考文献
Nazabadioko, Serge; Perez, Ramon J.; Brieva, Rosario; Gotor, Vicente
Tetrahedron Asymmetry, 1998 , vol. 9, # 9 p. 1597 - 1604
反应条件
1: HCl gas / 24 h / 0 °C 2: 0.5 N aq. HCl / ethanol / 48 h / 0 °C 3: 6 N aq. HCl / 10 h / Heating View Scheme
参考文献
Nazabadioko, Serge; Perez, Ramon J.; Brieva, Rosario; Gotor, Vicente
Tetrahedron Asymmetry, 1998 , vol. 9, # 9 p. 1597 - 1604
反应条件
1: CH2Cl2 / 24 h / -65 °C 2: Et3N / CH2Cl2 / 24 h / Ambient temperature 3: HCl gas / 24 h / 0 °C 4: 0.5 N aq. HCl / ethanol / 48 h / 0 °C 5: 6 N aq. HCl / 10 h / Heating View Scheme
参考文献
Nazabadioko, Serge; Perez, Ramon J.; Brieva, Rosario; Gotor, Vicente
Tetrahedron Asymmetry, 1998 , vol. 9, # 9 p. 1597 - 1604
反应条件
hydrogenchloride 10 h; Heating;
参考文献
Nazabadioko, Serge; Perez, Ramon J.; Brieva, Rosario; Gotor, Vicente
Tetrahedron Asymmetry, 1998 , vol. 9, # 9 p. 1597 - 1604
反应条件
hydrogenchloride; hydrogen; palladium dihydroxide in methanol 15 h; Ambient temperature; Yield given;
参考文献
Nazabadioko, Serge; Perez, Ramon J.; Brieva, Rosario; Gotor, Vicente
Tetrahedron Asymmetry, 1998 , vol. 9, # 9 p. 1597 - 1604
