2-(5-苯基-2H-1,2,3,4-四唑-2-基)-乙酸乙酯合成路线 （共 6 条）
反应条件
1: 89 percent / NaN3, NH4Cl / dimethylformamide / 17 h / Heating 2: 1.) EtONa / 1.) EtOH, reflux, 2.) EtOH, reflux, 16 h View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 27, # 12 p. 1565 - 1570
反应条件
ethanol; sodium 16 h; Heating;
参考文献
Journal of Heterocyclic Chemistry, , vol. 17, p. 637 - 640
反应条件
in acetonitrile T=25°C; dibenzo-18-crown-6; Yield given;
参考文献
Journal of Organic Chemistry USSR (English Translation), , vol. 18, p. 1738 - 1742
Zhurnal Organicheskoi Khimii, , vol. 18, # 9 p. 1981 - 1985
反应条件
sodium hydroxide 4 h; Heating;
参考文献
Maxwell, James R.; Wasdahl, Dan A.; Wolfson, Alan C.; Stenberg, Virgil I.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 12 p. 1565 - 1570
反应条件
1: 87 percent / conc. aq. NH3 / 3 h / 25 °C 2: 83 percent / phosphorus pentoxide / 0.67 h / 130 - 140 °C View Scheme
参考文献
Buzilova, S. R.; Brekhov, Yu. V.; Afonin, A. V.; Gareev, G. A.; Vereshchagin, L. I.
Journal of Organic Chemistry USSR (English Translation), 1989 , vol. 25, # 7.2 p. 1375 - 1379
Zhurnal Obshchei Khimii, 1989 , vol. 25, # 7 p. 1524 - 1528
反应条件
hydrazine hydrate in ethanol
8 h; Heating;
参考文献
Kothari; Singh; Parmar; Stenberg
Journal of Heterocyclic Chemistry, 1980 , vol. 17, # 7 p. 1393 - 1398
