1-(氯乙酰基)-4-(2-甲氧基苯基)哌嗪盐酸盐合成路线 (共 4 条)
反应条件
sodium hydroxide in benzene T=0°C; 3 h;
参考文献
Abou El-Ella, Dalal A.; Hussein, Mohammed M.; Serya, Rabah A.T.; Abdel Naby, Rana M.; Al-Abd, Ahmed M.; Saleh, Dalia O.; El-Eraky, Wafaa I.; Abouzid, Khaled A.M.
Bioorganic Chemistry, 2014 , vol. 54, p. 21 - 30
反应条件
triethylamine in dichloromethane T=0°C; 0.5 h; Inert atmosphere;
参考文献
Biswas, Swati; Hazeldine, Stuart; Ghosh, Balaram; Parrington, Ingrid; Kuzhikandathil, Eldo; Reith, Maarten E. A.; Dutta, Aloke K.
Journal of Medicinal Chemistry, 2008 , vol. 51, # 10 p. 3005 - 3019
参考文献
Journal of Labelled Compounds and Radiopharmaceuticals, , vol. 44, p. S21 - S23
反应条件
lithium aluminium tetrahydride in tetrahydrofuran; diethyl ether
T=40°C; 0.5 h;
参考文献
Colabufo, Nicola Antonio; Berardi, Francesco; Perrone, Roberto; Rapposelli, Simona; Digiacomo, Maria; Vanni, Michael; Balsamo, Aldo
Journal of Medicinal Chemistry, 2008 , vol. 51, # 23 p. 7602 - 7613