1-(二甲基氨基)-3-氟苯合成路线 （共 9 条）
参考文献
Journal of the Chemical Society, , p. 1808,1809
反应条件
[Pd(η3-1-Ph-allyl)(μ-Cl)]2; t-Bu Brett Phos; cesium fluoride in cyclohexane T=130°C; 12 h;
参考文献
Watson, Donald A.; Su, Mingjuan; Teverovskiy, Georgiy; Zhang, Yong; Garcia-Fortanet, Jorge; Kinzel, Tom; Buchwaldf, Stephen L.
Science, 2009 , vol. 325, # 5948 p. 1661 - 1664
反应条件
C27H36Cl2N2Zn; phenyl silane in tetrahydrofuran T=100°C; 20 h;
参考文献
Chemical Science, , vol. 4, # 5 p. 2127 - 2131
反应条件
N,N'-1,3-bis(2,6-diisopropylphenyl)-2,2-difluoroimidazoline; cesium fluoride in 1,4-dioxane T=110°C; 20 h; Sealed vial; Product distribution / selectivity;
参考文献
PRESIDENT AND FELLOWS OF HARVARD COLLEGE; RITTER, Tobias; TANG, Pingping
Patent: WO2012/142162 A2, 2012 ;
Location in patent: Page/Page column 24 ;
反应条件
potassium fluoride; C94H134O4P2Pd2; silver fluoride in cyclohexane T=130°C; 14 h; Sealed tube; Reagent/catalyst;
参考文献
Lee, Hong Geun; Milner, Phillip J.; Buchwald, Stephen L.
Journal of the American Chemical Society, 2014 , vol. 136, # 10 p. 3792 - 3795
反应条件
methanol T=170°C; und Erhitzen des Reaktionsprodukts mit Acetanhydrid;
参考文献
Journal of the Chemical Society, , p. 766,767
反应条件
T=58.3 - 91.4°C; Rate constant;
参考文献
Journal of the Chemical Society, , p. 3194,3196
反应条件
water; trichlorophosphate Yield given. Multistep reaction;
参考文献
Meyer, Walter E.; Tomcufcik, Andrew S.; Chan, Peter S.; Emma, John E.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 12 p. 1705 - 1710
