7,8-二羟基-4-甲基香豆素合成路线 (共 29 条)
反应条件
1: cyclohexyl(triphenyl)phosphonium bromide With n-butyllithium in tetrahydrofuran; hexane T=-40°C; 0.5 h; 2: 4-methylchromene-2,7,8-trione in tetrahydrofuran; hexane T=-40°C; 1 h; Further stages.;
参考文献
Journal of the Chemical Society. Perkin Transactions 1, , # 22 p. 3073 - 3079
反应条件
1: triphenyl-cyclopentylphosphonium bromide With n-butyllithium in tetrahydrofuran; hexane T=0°C; 0.5 h; 2: 4-methylchromene-2,7,8-trione in tetrahydrofuran; hexane T=0°C; 1 h; Further stages.;
参考文献
Journal of the Chemical Society. Perkin Transactions 1, , # 22 p. 3073 - 3079
反应条件
diphenyl acetylene; methyl (triphenylphosphoranylidene)acetate in dichloromethane 12 h; Heating;
参考文献
Journal of Chemical Research, Miniprint, , # 3 p. 826 - 852
反应条件
rat liver microsomes; tris(hydroxymethyl)methylamine hydrochloride in water T=37°C; Deacetylation; pH=7.5; Enzyme kinetics;
参考文献
Bioorganic and Medicinal Chemistry, , vol. 8, # 1 p. 233 - 237
反应条件
in dichloromethane T=-10°C; 4 h;
参考文献
Journal of the Chemical Society. Perkin Transactions 1, , # 22 p. 3073 - 3079
反应条件
diphenyl acetylene in dichloromethane 12 h; Heating;
参考文献
Journal of Chemical Research, Miniprint, , # 3 p. 826 - 852
反应条件
diphenyl acetylene in dichloromethane 12 h; Heating;
参考文献
Journal of Chemical Research, Miniprint, , # 3 p. 826 - 852
反应条件
in dichloromethane T=20°C; 0.5 h;
参考文献
Journal of the Chemical Society. Perkin Transactions 1, , # 22 p. 3073 - 3079
反应条件
in dichloromethane T=20°C; 24 h;
参考文献
Journal of the Chemical Society. Perkin Transactions 1, , # 22 p. 3073 - 3079
反应条件
diethyl ether; sulfuric acid
参考文献
Zhurnal Obshchei Khimii, , vol. 25, p. 815,819; engl. Ausg. S. 781, 785