1: 81 percent / BH3*THF, TFA 2: DCC 3: DDQ / toluene / Heating 4: 1.) Hg(OTFA)2, 2.) KI, 3.) I2 5: Pd2(dba)3, P(o-tolyl)3, K2CO3 / toluene / Heating 6: Zn, AcOH 7: DCC 8: 93 percent / Zn, AcOH / ethyl acetate 9: 82 percent / Et3N, DMAP 10: 91 percent / Bu3P / benzene / 60 °C 11: 3-n-butyl-1,2-benzisothiazole-1,1-dioxide oxide / 48 h 12: NaBH4, AcOH 13: 87 percent / H2 / Pd/C / methanol / 0.25 h / 760 Torr View Scheme