1: DCC 2: DDQ / toluene / Heating 3: 1.) Hg(OTFA)2, 2.) KI, 3.) I2 4: Pd2(dba)3, P(o-tolyl)3, K2CO3 / toluene / Heating 5: Zn, AcOH 6: DCC 7: 93 percent / Zn, AcOH / ethyl acetate 8: 82 percent / Et3N, DMAP 9: 91 percent / Bu3P / benzene / 60 °C 10: 3-n-butyl-1,2-benzisothiazole-1,1-dioxide oxide / 48 h 11: NaBH4, AcOH 12: 87 percent / H2 / Pd/C / methanol / 0.25 h / 760 Torr View Scheme