6-溴乙酰基-2-二甲氨基萘合成路线 （共 3 条）
反应条件
phosphorous acid diethyl ester; triethylamine in tetrahydrofuran 0 deg C; RT, 6 h;
参考文献
Diwu, Zhenjun; Beachdel, Christopher; Klaubert, Dieter H.
Tetrahedron Letters, 1998 , vol. 39, # 28 p. 4987 - 4990
反应条件
1: conc. sulfuric acid; bromine / tetrahydrofuran / 4 h / 20 °C 2: 110 mg / diethyl phosphite; DIPEA / tetrahydrofuran / 20 °C View Scheme
参考文献
Chemical communications (Cambridge, England), , # 17 p. 1912 - 1913
反应条件
1: 86 percent / 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone / hexane / 16 h / 20 °C 2: conc. sulfuric acid; bromine / tetrahydrofuran / 4 h / 20 °C 3: 110 mg / diethyl phosphite; DIPEA / tetrahydrofuran / 20 °C View Scheme
参考文献
Chemical communications (Cambridge, England), , # 17 p. 1912 - 1913
