乙酰溴-Alpha-D-葡萄糖酮酸甲基酯合成路线 （共 53 条）
反应条件
1: pyridine 2: 82 percent / HBr / acetic acid View Scheme
参考文献
Tetrahedron Letters, , vol. 41, # 45 p. 8829 - 8834
反应条件
1: 1H-imidazole / N,N-dimethyl-formamide; tetrahydrofuran / 0 - 20 °C 2: potassium hydroxide / methanol / 0 - 20 °C View Scheme
参考文献
Carbohydrate Research, , vol. 370, p. 19 - 23
反应条件
1: potassium carbonate; methanol / 6 h / 20 °C 2: 1H-imidazole / N,N-dimethyl-formamide; tetrahydrofuran / 0 - 20 °C 3: potassium hydroxide / methanol / 0 - 20 °C View Scheme
参考文献
Carbohydrate Research, , vol. 370, p. 19 - 23
反应条件
1: HBr; HOAc View Scheme
参考文献
Carbohydrate Research, , vol. 342, # 14 p. 2132 - 2137
反应条件
1: D-glcUA With iodine; acetic anhydride 2: methanol
参考文献
Carbohydrate Research, , vol. 344, # 5 p. 599 - 605
→
34096-83-8(2S,3S,4S,5R,6R)-6-[[(3S,4aR,6aR,6bS,8aS,11S,12aR,14aR,14bS)-11-羧基-4,4,6a,6b,8a,11,14b-七甲基-14-氧代-2,3,4a,5,6,7,8,9,10,12,12a,14a-十二氢-1H-苉-3-基]氧基]-3,4,5-三羟基四氢吡喃-2-羧酸
反应条件
sodium hydroxide; mercury(II) cyanide 1.) toluene, reflux, 5 h, 2.) 50percent aq. EtOH, reflux, 3 h; Yield given. Multistep reaction;
参考文献
Mizutani; Kuramoto; Tamura; Ohtake; Doi; Nakaura; Tanaka
Bioscience, biotechnology, and biochemistry, 1994 , vol. 58, # 3 p. 554 - 555
反应条件
silver carbonate in toluene T=20 - 75°C; Koenigs-Knorr synthesis; 21 h; Inert atmosphere;
参考文献
Moench, Bettina; Gebert, Antje; Emmerling, Franziska; Becker, Roland; Nehls, Irene
Carbohydrate Research, 2012 , vol. 352, p. 186 - 190
反应条件
methanol; mercury(II) cyanide
参考文献
Helferich; Berger
Chemische Berichte, 1957 , vol. 90, p. 2492,2495
反应条件
silver carbonate; benzene
参考文献
Wotiz et al.
Journal of the American Chemical Society, 1959 , vol. 81, p. 1704,1706
反应条件
1: 72 percent / Ag2CO3 / benzene / 48 h / Ambient temperature 2: 83 percent / NaBH4, PdCl2 / methanol / 2 h / 0 °C View Scheme
参考文献
Numazawa, Mitsuteru; Nagaoka, Masao; Tsuji, Masachika; Osawa, Yoshio
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 1 p. 121 - 125
