1-乙炔基-3-(甲硫基)苯合成路线 （共 3 条）
反应条件
sodium hydride in benzene 1 h; Heating;
参考文献
Chowdhury, Morshed Alam; Dong, Ying; Chen, Qiao-Hong; Abdellatif, Khaled R.A.; Knaus, Edward E.
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 4 p. 1948 - 1956
反应条件
1: 1.) t-BuLi, 2.) I2 / 1.) Et2O, pentane, -75 deg C, 30 min, 2.) Et2O, -75 deg C, 10 min; -20 deg C, 10 min 2: 98 percent / Et3N, CuI / Pd(PPh3)2Cl2 / toluene / 2 h / 20 °C 3: 99 percent / TBAF / tetrahydrofuran / 0.75 h / 20 °C View Scheme
参考文献
Mongin, Olivier; Papamicael, Cyril; Hoyler, Nicolas; Gossauer, Albert
Journal of Organic Chemistry, 1998 , vol. 63, # 16 p. 5568 - 5580
反应条件
1: 98 percent / Et3N, CuI / Pd(PPh3)2Cl2 / toluene / 2 h / 20 °C 2: 99 percent / TBAF / tetrahydrofuran / 0.75 h / 20 °C View Scheme
参考文献
Mongin, Olivier; Papamicael, Cyril; Hoyler, Nicolas; Gossauer, Albert
Journal of Organic Chemistry, 1998 , vol. 63, # 16 p. 5568 - 5580
