2-(4-苯基-哌嗪-1-基)-乙胺合成路线 （共 7 条）
反应条件
lithium aluminium tetrahydride in tetrahydrofuran Ambient temperature;
参考文献
Perrone; Berardi; Leopoldo; Tortorella; Lograno; Daniele; Govoni
Farmaco, 1994 , vol. 49, # 9 p. 567 - 572
反应条件
hydrazine in ethanol T=20°C; 24 h;
参考文献
Dutta, Aloke K.; Venkataraman, Sylesh K.; Fei, Xiang-Shu; Kolhatkar, Rohit; Zhang, Shijun; Reith, Maarten E.A.
Bioorganic and Medicinal Chemistry, 2004 , vol. 12, # 16 p. 4361 - 4373
反应条件
1: K2CO3 / dimethylformamide / 2 h / 80 °C 2: hidrazine / ethanol / 5 h / 70 °C View Scheme
参考文献
Dutta, Aloke K; Fei, XiangShu; Reith, Maarten E.A
Bioorganic and Medicinal Chemistry Letters, 2002 , vol. 12, # 4 p. 619 - 622
反应条件
hydrogen bromide in acetic acid 1 h; Ambient temperature;
参考文献
Nakao, Kazuya; Shimizu, Ryo; Kubota, Hitoshi; Yasuhara, Mikiko; Hashimura, Yoshimasa; Suzuki, Toshikazu; Fujita, Toshio; Ohmizu, Hiroshi
Bioorganic and Medicinal Chemistry, 1998 , vol. 6, # 6 p. 849 - 868
参考文献
Cerkovnikov; Stern
Arhiv za Kemiju, 1946 , vol. 18, p. 12,24
Chem.Abstr., 1948 , p. 1938
反应条件
1: With acetic acid in 1,2-dichloro-ethane T=20°C; 1 h; 2: With sodium cyanoborohydride in methanol; 1,2-dichloro-ethane Further stages.;
参考文献
Biswas, Swati; Zhang, Suhong; Fernandez, Fernando; Ghosh, Balaram; Zhen, Juan; Kuzhikandathil, Eldo; Reith, Maarten E. A.; Dutta, Aloke K.
Journal of Medicinal Chemistry, 2008 , vol. 51, # 1 p. 101 - 117
参考文献
Chakrabarti, Jiban K.; Horsman, Linda; Hotten, Terrence M.; Pullar, Ian A.; Tupper, David E.
Journal of Medicinal Chemistry, 1980 , vol. 23, # 8 p. 878 - 884
